A double-blinded randomized clinical trial of pain perception during orthodontic treatment

Abstract Introduction Orthodontic movement can cause painful symptoms, especially in the early stages of treatment. Objective This study aimed to compare performance chewing gum and ibuprofen pain control during initial period orthodontic Material method A randomized blind clinical trial, with an allocation ratio 1:1, was developed patients aged ≥18 years old. The sample size established considering a significance level 5% test power 80%, resulting minimum 30 volunteers per group (n=90). Participants were paired regarding sex, age, severity malocclusion, defined by Dental Health Component (DHC) Index Treatment Need (IOTN), crowding, determined Little’s irregularity index. randomly allocated three groups: Group I (control) placebo; II gum; III Ibuprofen. Pain perception evaluated Visual Analog Scale (VAS) first 24, 36, 48 hours after activation appliance. data analyzed generalized linear models for repeated measures time. Result No statistically significant difference (p>0.05) observed among groups methods therapy post-activation. Conclusion There no used